Research Topics
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- Optical Chemo- and Biosensors
- Nano and micrometer sized (magnetic) sensor particles
- Optical glucose sensors
- New indicator dyes for optical sensing
- Optical multi-analyte sensors
- Integrated optical sensors based on organic optoelectronic components
- Time-resolved imaging and microscopy with lumincescent indicators
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Research projects - ongoing
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ERA-NET: Magnetic Nanosensor Particles with Luminescence Up-conversion Capability |
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The joined research project aims to investigate multi-functional nano particles for optical chemical and biochemical sensing.
The beneficial functionalities combined in one nano particle include: magnetism, luminescence up-conversion, sensing and light harvesting. |
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ISOTEC- Integrated organic optical sensor arrays |
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The research project, as a part of the ISOTEC Cluster project, aims to establish an integrated organic optical sensor platform
suitable for the parallel detection of multiple parameters in an array format. |
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Indicators for long-wave excitable luminescent sensors |
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The project is focused on designing luminescent sensors which can be interrogated with long-wave emitting light sources. To realize this, novel red-light excitable oxygen indicators and fluorescent pH indicators are synthesized and characterized. |
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Optimization of Optical Glucose Sensors for Monitoring Critically Ill Patients |
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The continuous monitoring of blood glucose concentrations is beneficial to reduce the
morbidity and mortality of critically ill patients. Therefore, an optical enzymatic glucose sensor
was developed. |
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Comprehensive Study of the Effects of Sterilisation procedures on Sensor Materials |
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Sterilisation is a main precondition for the application of sensors and bio-sensors in different
application areas. However, data of the effects of sterilisation on the sensor materials is spares.
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Nano- and microsensors for the application in biofilms |
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Due to the ubiquity of biofilms in nature it is of great interest
to understand their metabolism and the interaction of the different
parts and organisms inside a biofilm. For this porpous optical thinlayer
and nano sensors are used to investigate the oxygenation and other
parameters with high spatial resolution on the surface or even within
the biofilm itself. |
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Research projects - completed
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Lise Meitner-Program: Optical multi-analyte sensors |
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This project is aimed to realize optical multy-analyte sensors that are capable of simultaneous measurement of 4 parameters. Three chemical parameters (pH, pO2 and pCO2/pNH3/salinity) are determined and combined with optical compensation for the temperature effects. |
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- Closed Loop Insulin Infusion for Critically Ill Patients
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The research group is envolved in this EU project of 6th Framework Programme.
In breave, Clinicip has the aim to develop a low-risk monitoring and control
system which allows to maintain metabolic control of critically ill patients in the
intensive care unit. |
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Optical ammonia sensors with detection limits in the ppb range |
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Sensitive and selective sensor materials for on-line monitoring of gaseous
and dissolved ammonia are developed in this research project. The survey of
the ammonia concentration in drinking and surface waters for environmental
analysis, fish farms. |
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Sugar responsive fluorescent nanospheres |
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In this research project we develop sugar responsive nanosensors based
on the osmotic presure driven swelling of an amphiphilic polymer. The volume
transition is tracked by resonance energy transfer (RET) of co-polymerized
donor and acceptor dyes. |
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Microsphere Sedimentation Bioarrays |
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A new measurement platform to analyze multiple assays in parallel in a
single well of a standard microplate is developed..The approach is based
on optically addressable encoded magnetic microbeads as carriers for a
series of bioassays. |
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Screening of Microcolony chip with optical sensor layers |
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Directed evolution has become a widely used technique in enzyme
development. It leads often to vast libraries of potential new variants which
have to be examined. High throughput methods offer the possibility to examine
huge amounts of sample in parallel. |
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Database |
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Database of fluorescent dyes, properties and application |
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The objective of Fluorophores.org is to provide an accurate, high valuable
and comprehensive catalogue of fluorescent (luminescent) dyes, their properties
and application. The initiators intend to create a usefull tool for scientists working
with fluorescence. |
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Cooperations
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Institut für Medizinische Systemtechnik und Gesundheitsmanagement - MSG
Institut für Chemische Prozeßentwicklung und -kontrolle - CPK
Institut für Nanostrukturierte Materialien und Photonik - NMP
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Center for Medical Research, ZMF |
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Equipment
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Malvern, Zetasizer nano ZS |
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Fluorescence Microscope |
Zeiss Axiovert 25 |
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Time resolved camera system |
PCO, SensiCam |
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Microplate reader |
BMG Labtech, Fluostar |
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Spectrophotometer |
Varian, Carry 50 |
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Fluorescence Spectrometer |
Perkin Elmer LS 50 B |
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Fluorescence Spectrometer |
Hitachi F7000 |
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Fiber optical luminescence sensing devices |
Presens, Fibox |
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Graz University of Technology - Institute of Analytical Chemistry & Food Chemistry - Stremayrgasse 9 - 8010 Graz - Austria
